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Confluent papules may coalesce into plaques; when viewed by diascopy, these plaques have an “apple-jelly” deposit representing cellular infiltrates. 2), raised the hypothesis of cutaneous sarcoidosis, which was confirmed by histopathological examination. Although not specific for cutaneous sarcoidosis, as it can also be seen on other granulomatous conditions such as granuloma annulare, this ‘apple jelly’ Discussion. %PDF-1.6 %���� 2T�1�5&� 7!�A�"�D��[�8�.�i�F�vm�T�"#!�d��k��L�>$�Yg ���t���U������o�];;u=q_Ӊ�?������2r�'��7�TBO���c8RBO�� ��.��CF/�|�o��&GGIDz^�=���i�O����|�A�0Z��,-��1���qmO��`}����#��f���Cz�76���g?�hv�/���Q�T����Ж��Q�F_�ތ*[9:��/_�|GG;�{���GB/���4O��S7�����t������{���{AG��"s7�MXmQ9� g�����UD ���}�x���uE4!5���fvV�������8����[D0@)�K�I3P_�6{Q����z2�W�� 8�j|���'����*\5�n�KW�ActP�,����FG���@��v���E���~lΡ��>��C�M���$ �_r_��'����dh��,=��C�]M�P"�h��BC�)�(�6�^�2:J8���z�����+�-=�S#�T1g\�z�]C����P�5���cI���yRX�D��W���AFk3 ����j�(:��o�����-�uÃ68|��. Seminars in respiratory and critical care medicine, By clicking accept or continuing to use the site, you agree to the terms outlined in our. Hemorrhagic lesions and nonvascular lesions do not blanch("negative diascopy"); inflammatory lesions do("positive diascopy"). 277 0 obj <>/Filter/FlateDecode/ID[<1719E82A961C3641B6CF822A23AC0340>]/Index[245 60]/Info 244 0 R/Length 147/Prev 1068931/Root 246 0 R/Size 305/Type/XRef/W[1 3 1]>>stream Diascopy, by showing a yellowish nodule-like aspect (Fig. Sign Up or Log In to join the discussion. https://en.wikipedia.org/w/index.php?title=Diascopy&oldid=784119407, Creative Commons Attribution-ShareAlike License, This page was last edited on 6 June 2017, at 15:30. Diascopy is sometimes used to identify sarcoid skin lesions, which, when tested, turn an apple jelly color. Easy Learning Medical Videos 769 ... 7:31. h��X�o�6�W�ˊ"�KE��8M�N��m� ��ڬ#L�I.�����$;r�8N������f��#B�U@Dc��� ��Di_I�P�7 :Ĺ"���p��A� � BI It is used to determine whether a lesion is vascular (inflammatory or congenital), nonvascular (nevus), or hemorrhagic (petechia or purpura). 1). Thus, they are frequently found in cutaneous sarcoidosis and lupus vulgaris, probably mirroring the classically described “apple-jelly” sign observed upon diascopy. 0 Apple jelly nodules -fmge/mci screning test - Duration: 0:32. 304 0 obj <>stream

The diascopy of the lesions in sarcoidosis, not described by the authors in any of their cases, reveals an apple jelly, nodule-like appearance indicating their granulomatous etiology. Therefore, under appropriate clinical correlation, dermoscopy can be a valuable non-invasive tool for the diagnosis of cutaneous sarcoidosis. 1), revealing a yellow-brown granulomatous appearance resembling apple-jelly (Fig.

245 0 obj <> endobj Hemorrhagic lesions and nonvascular lesions do not blanch ("negative diascopy"); inflammatory lesions do ("positive diascopy"). You are currently offline. Presentations, Signs of Activity, and Differential Diagnosis of Vitiligo. A 43-year-old woman presented with erythematous papules and plaques on the forehead evolving in the previous 3 months (Fig. h�bbd```b``6� `v2�d��JA�&�T��j9 R� Dʱ�H�@ɸL�������e���C �Z��� �)LƁ��M �¨w�`��'�� @&D���$��?��~H��j���E�F�AG�g`2x` s;� No abstract text is available yet for this article. The pressure from the glass slide application eliminates the characteristic erythema (Fig. Rewise MD … > �-� "Apple Jelly" Sign: Diascopy in Cutaneous Sarcoidosis. 2).

Sarcoidosis is a multisystemic granulomatous disease, a histologically evident characteristic shared by its cutaneous lesions. Find Full Text Links for this Article. Additional links. Diascopy is a test for blanchability performed by applying pressure with a finger or glass slide and observing color changes.[1]. Semantic Scholar is a free, AI-powered research tool for scientific literature, based at the Allen Institute for AI. This granulomatous nature can be elicited by diascopy. This granulomatous nature can be elicited by diascopy. Some features of the site may not work correctly.

On applying pressure with a glass slide, the erythematous color of the papules is mitigated and the yellow brown color can be more easily appreciated.
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Diogo Matos, Ricardo Coelho. Involvement of the glans may occur. You are not logged in. Hemorrhagic lesions and nonvascular lesions do not blanch ("negative diascopy"); inflammatory lesions do ("positive diascopy"). Acta Médica Portuguesa 2015, 28 (3): 394.